New mouse model mimics earliest stages of Alzheimer’s disease

Determine 1: The brand new RIKEN mannequin mice present hallmark indicators of Alzheimer’s illness within the mind—each amyloid plaques (blue) and inflammatory alerts (inexperienced and crimson). Credit score: RIKEN Heart for Mind Science

Drug hunters hoping to forestall or delay the onset of Alzheimer’s illness take notice—a brand new mouse mannequin developed at RIKEN presents a robust platform for evaluating potential therapies designed to fight the neurodegenerative illness in its earliest levels.

Alzheimer’s illness is globally the commonest neurodegenerative dysfunction. Many compounds that confirmed promise in mice fashions of the illness subsequently flopped in medical trials on folks. One purpose

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